
Obesity Linked to Prostate Cancer
(Ivanhoe Newswire) -- Obese men are at a higher risk of their prostate cancer worsening, even when treated to suppress tumor growth, according to a study.
"Over the past decades, there has been increasing prevalence of obesity in the U.S. and Europe, and a high rate of prostate cancer that is the second-most lethal cancer for men," Christopher J Keto, M.D., a urologic fellow at Duke University Medical Center and lead author of the study was quoted as saying.
Roughly one in six men will be diagnosed with prostate cancer during his lifetime, according to the American Cancer Society, and about one in three men is obese.
Keto and Colleagues identified 287 men whose disease prostates had been removed. The men were also give androgen deprivation therapy (ADT), a treatment preventing tumor growth.
Men who were overweight had a three-fold increased risk of their cancer spreading to the bone compared to normal weight men, and obese men had a five-fold increase.
"We think perhaps obese men may require additional ADT," Keto said. "The dose is the same regardless of weight, while most drugs are dosed according to weight."
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